PDRN

A skin-renewing DNA-based active for a visibly smoother, more resilient complexion.

Why PDRN ?

Renew

Supports a fresher, more revitalized look for tired or stressed-looking skin.

Soothe

Helps skin look and feel calm and comfortable, ideal for recovery-focused and sensitive-looking skin formulas.

Smooth

Contributes hydration and a smoother, more resilient-looking skin surface.

When to Use

Best considered when developing recovery-focused and anti-aging skincare formulas where a fresher, smoother and more resilient-looking complexion is desired.

Better Together

Explore ingredient that can completed PDRN in a formulation

Become Formula

See how PDRN can become different product experiences

Serum

Balm

Cream

Gel

Everything you need to know about PDRN

PDRN (Polydeoxyribonucleotide) is a complex of DNA fragments, most commonly derived from salmon, that has become a signature ingredient in modern Korean skincare. It supports a revitalized, resilient-looking complexion, helps skin look and feel calm and comfortable, and contributes to hydration and a smoother, more refined skin surface. It is a popular choice for anti-aging, skin-recovery and conditioning formulas.

What are the benefits of PDRN for the skin?

Early research suggests that PDRN may support the skin barrier, hydration, and regenerative processes. Topical results, however, depend heavily on ingredient source, molecular characteristics, delivery system, and the finished formula.

When should you use PDRN

Skincare containing PDRN can be used in both morning and evening routines. Consistent use matters more than choosing a particular time of day. Apply products from the lightest to the richest texture, finishing with moisturizer. In the morning, complete the routine with sunscreen to help protect the results of your skincare.

Is PDRN suitable for sensitive skin

The suitability of PDRN for sensitive skin depends on ingredient source, purity, delivery system, and the finished formula. Standardization matters because this category is still developing. Choose products with clear ingredient identity and safety documentation. Patch test before regular use, especially after a procedure or when the skin barrier is fragile.

Can PDRN be used with other actives?

PDRN can be used in formulas with Hyaluronic Acid, Panthenol, Peptides, and Ceramide NP. This combination does not require a special waiting period unless the product directions say otherwise. Begin with a simple routine so the skin’s response is easier to observe. Avoid introducing several new products at once, especially after a procedure.

Turn PDRN into your next formulation

Simulate Your Product